Normal Reference Range for Serum TSH, Free T4, Total T4, and Total T3 on Roche® Platforms in Basrah, Iraq

Alibrahim, Nassar Taha and Odhaib, Samih Abed and Alhamza, Ali Hussain and Almomin, Ammar Mohammed Saeed and Zaboon, Ibrahim Abbood and Hussein, Rudha Naser and Kadhim, Muayad Baheer and Mohammed, Adel Gassab and Al-Waeli, Dheyaa Kadhim and Nwayyir, Hussein Ali and Alidrisi, Haider Ayad and Hussein, Ibrahim Hani and Altemimi, Mahmood Thamer and Imran, Husam Jihad and Mansour, Abbas Ali (2021) Normal Reference Range for Serum TSH, Free T4, Total T4, and Total T3 on Roche® Platforms in Basrah, Iraq. Journal of Pharmaceutical Research International, 33 (45A). pp. 147-155. ISSN 2456-9119

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Official URL: https://doi.org/10.9734/jpri/2021/v33i45A32727

Abstract

Background: Thyroid function tests are mandatory in clinical practice because symptoms and signs are not reliable to discriminate between various types of thyroid disease.

Aim: The aim of this study was to determine assay-specific reference range for serum free T4, total T4, total T3 and TSH among healthy non-pregnant adult cohort for Roche® platforms in Basrah (Southern Iraq) from single laboratory in a tertiary center using indirect approach of the available data.

Methods: A Cross sectional study for non-pregnant adults 19 years and above. Sera were analyzed by using cobs e411 for thyroid functions tests.

Results: Total enrolled persons were 10,078. The 95% reference intervals for TSH were 0.20-6.50 μIU/mL, which increased with age though not linear, for free T4 were 0.8-1.70 ng/dL, for total T4 were 3.78-15.33 μg/dL, and for total T3 were 0.80-2.50 ng/mL.

Colcusion: Cobs e411(Roche® analytical platform) analyzer reference range for thyroid function cannot be applied for Iraqi population .

Item Type:	Article
Subjects:	Digital Academic Press > Medical Science
Depositing User:	Unnamed user with email support@digiacademicpress.org
Date Deposited:	01 Feb 2023 07:51
Last Modified:	09 Jul 2024 07:32
URI:	http://science.researchersasian.com/id/eprint/80

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